Changes in version 2.0.0                        

  - Added a unified table workflow with sample/feature metadata
    validation, batch-aware blank filtering, missing-value handling,
    QC-RLSC/PQN normalization, and processing records.
  - Added two-group comparisons using Welch or Wilcoxon tests with
    Benjamini-Hochberg adjusted p-values.
  - Added self-contained HTML QC reports and complete result bundles
    with original inputs, processed tables, feature/sample metadata, QC
    summaries, and settings.
  - MS1 annotation now searches CEU Mass Mediator through the optional
    cmmr package. The legacy annotation database and external
    data-release downloader were removed.
  - Retained SCIEX/Qtrap processing, targeted calibration, robust sample
    QC, PCA, heatmaps, LC-MS feature plots, spectrum plotting, and MSP
    writing.
  - Removed the legacy OmicsData S4/synthetic-data system, generic
    predictive modeling, feature selection, graph/enrichment displays,
    raw-file MS/MS inspection/conversion, and incomplete or duplicate
    app screens. These are intentional breaking API changes from CRAN
    version 1.1.7.
  - Reduced required external dependencies and replaced the app wrapper
    with the standard Shiny launcher. Excel import and specialized
    exports are optional.
  - Updated package authorship. Amrita Cheema is the designated
    maintainer at metabolomics@georgetown.edu.
  - Added the hex logo and horizontal workflow figure. Standalone QC
    reports omit personal credits while preserving author metadata in
    exported settings.